| LIGA 2021/2022 | ||||
| 1º Fecha | ||||
| 13-ago-2021 | Valencia | Valencia | 1 | Soler (P) |
| Getafe | 0 | |||
| 14-ago-2021 | Pamplona | Osasuna | 0 | |
| Español | 0 | |||
| 14-ago-2021 | Palma de | Mallorca | 1 | Olivan |
| Gran Mallorca | Betis | 1 | Reina (A) | |
| 14-ago-2021 | Cadiz | Cadiz | 1 | Espino |
| Levante | 1 | Morales | ||
| 14-ago-2021 | Vitoria | Alaves | 1 | Joselu (P) |
| Real Madrid | 4 | Benzema (2), Nacho, Vinicius Junior | ||
| 15-ago-2021 | Vigo | Celta | 1 | Aspas (P) |
| Atletico Madrid | 2 | Correa (2) | ||
| 15-ago-2021 | Barcelona | Barcelona | 4 | Pique, Braithwaite (2), Sergi Roberto |
| Real Sociedad | 2 | Lobete, Oyarzabal | ||
| 15-may-2021 | Sevilla | Sevilla | 3 | En Nesyri (P), Lamela (2) |
| Rayo Vallecano | 0 | |||
| 16-ago-2021 | Villarreal | Villarreal | 0 | |
| Granada | 0 | |||
| 16-ago-2021 | Elche | Elche | 0 | |
| Athletic Bilbao | 0 | |||
| 2º Fecha | ||||
| 20-ago-2021 | Sevilla | Betis | 1 | Juanmi |
| Cadiz | 1 | Negredo (P) | ||
| 21-ago-2021 | Vitoria | Alaves | 0 | |
| Mallorca | 1 | Fer Niño | ||
| 21-ago-2021 | Granada | Granada | 1 | Suarez |
| Valencia | 1 | Soler (P) | ||
| 21-ago-2021 | Barcelona | Español | 0 | |
| Villarreal | 0 | |||
| 21-ago-2021 | Bilbao | Athletic Bilbao | 1 | Martinez |
| Barcelona | 1 | Depay | ||
| 22-ago-2021 | San Sebastian | Real Sociedad | 1 | Oyarzabal (P) |
| Rayo Vallecano | 0 | |||
| 22-ago-2021 | Madrid | Atletico Madrid | 1 | Correa |
| Elche | 0 | |||
| 22-ago-2021 | Valencia | Levante | 3 | Roger Marti, Campaña |
| Real Madrid | 3 | Bale, Vinicius Junior (2) | ||
| 23-ago-2021 | Getafe | Getafe | 0 | |
| Sevilla | 1 | Lamela | ||
| 23-ago-2021 | Pamplona | Osasuna | 0 | |
| Celta | 0 | |||
| 3º Fecha | ||||
| 27-ago-2021 | Palma | Mallorca | 1 | Rodriguez |
| de Mallorca | Español | 0 | ||
| 27-ago-2021 | Valencia | Valencia | 3 | Wass, Soler, Goncalo Guedes |
| Alaves | 0 | |||
| 28-ago-2021 | Vigo | Celta | 0 | |
| Athletic Bilbao | 1 | Williams | ||
| 28-ago-2021 | San Sebastian | Real Sociedad | 1 | Barrenetxea |
| Levante | 0 | |||
| 28-ago-2021 | Elche | Elche | 1 | Roco |
| Sevilla | 1 | En Nesyri | ||
| 28-ago-2021 | Sevilla | Betis | 0 | |
| Real Madrid | 1 | Carvajal | ||
| 29-ago-2021 | Barcelona | Barcelona | 2 | Sergi Roberto, Depay |
| Getafe | 1 | Ramirez | ||
| 29-ago-2021 | Cadiz | Cadiz | 2 | Alex (2, 1P) |
| Osasuna | 3 | Kike (P), Torres (P), Garcia | ||
| 29-ago-2021 | Madrid | Rayo Vallecano | 4 | Garcia, Trejo (P), Nteka, Comesaña |
| Granada | 0 | |||
| 29-ago-2021 | Madrid | Atletico Madrid | 2 | Suarez, Mandi (A) |
| Villarreal | 2 | Trigueros, Groeneveld | ||
| 4º Fecha | ||||
| 11-sep-2021 | Valencia | Levante | 1 | Marti (P) |
| Rayo Vallecano | 1 | Guardiola | ||
| 11-sep-2021 | Bilbao | Athletic Bilbao | 2 | Dani Vivian, Williams |
| Mallorca | 0 | |||
| 12-sep-2021 | Barcelona | Español | 1 | De Tomas |
| Atletico Madrid | 2 | Carrasco, Lemar | ||
| 12-sep-2021 | Pamplona | Osasuna | 1 | Moncayola |
| Valencia | 4 | Gomez, Hernandez (A), Guedes, Alderete | ||
| 12-sep-2021 | Cadiz | Cadiz | 0 | |
| Real Sociedad | 2 | Oyarzabal (2, 1P) | ||
| 12-sep-2021 | Madrid | Real Madrid | 5 | Benzema (3, 1P), Vinicius Junior, Camavinga |
| Celta | 2 | Santi Mina, Cervi | ||
| 13-sep-2021 | Getafe | Getafe | 0 | |
| Elche | 1 | Perez | ||
| 13-sep-2021 | Granada | Granada | 1 | Suarez |
| Betis | 2 | Rodri, Canales | ||
| 21-dic-2021 | Sevilla | Sevilla | 1 | Gomez |
| Barcelona | 1 | Araujo | ||
| 21-dic-2021 | Villarreal | Villarreal | 5 | Moreno (2), Dia (2), Pino |
| Alaves | 2 | Pons, Joselu | ||
| 5º Fecha | ||||
| 17-sep-2021 | Vigo | Celta | 1 | Mina |
| Cadiz | 2 | Lozano, Espino | ||
| 18-sep-2021 | Madrid | Rayo Vallecano | 3 | Trejo (P), Ciss, Garcia |
| Getafe | 0 | |||
| 18-sep-2021 | Madrid | Atletico Madrid | 0 | |
| Athletic Bilbao | 0 | |||
| 18-sep-2021 | Elche | Elche | 1 | Perez |
| Levante | 1 | Morales | ||
| 18-sep-2021 | Vitoria | Alaves | 0 | |
| Osasuna | 2 | Garcia, Torres (P) | ||
| 19-sep-2021 | Palma | Mallorca | 0 | |
| de Mallorca | Villarreal | 0 | ||
| 19-sep-2021 | San Sebastian | Real Sociedad | 0 | |
| Sevilla | 0 | |||
| 19-sep-2021 | Sevilla | Betis | 2 | Pedrosa (A), Fekir |
| Español | 2 | Vidal, Cabrera | ||
| 19-sep-2021 | Valencia | Valencia | 1 | Duro |
| Real Madrid | 2 | Vinicius Junior, Benzema | ||
| 20-sep-2021 | Barcelona | Barcelona | 1 | Araujo |
| Granada | 1 | Duarte | ||
| 6º Fecha | ||||
| 21-sep-2021 | Getafe | Getafe | 1 | Oblak (A) |
| Atletico Madrid | 2 | Suarez (2) | ||
| 21-sep-2021 | Bilbao | Athletic Bilbao | 1 | Ciss (A) |
| Rayo Vallecano | 2 | A. Garcia, R. Garcia | ||
| 21-sep-2021 | Valencia | Levante | 0 | |
| Celta | 2 | Aspas, Mendez | ||
| 22-sep-2021 | Barcelona | Español | 1 | De Tomas (P) |
| Alaves | 0 | |||
| 22-sep-2021 | Sevilla | Sevilla | 3 | Gomez, Montiel, Mir |
| Valencia | 1 | Duro | ||
| 22-sep-2021 | Madrid | Real Madrid | 6 | Benzema (2), Asensio (3), Isco |
| Mallorca | 1 | Lee Kang In | ||
| 22-sep-2021 | Villarreal | Villarreal | 4 | Pino, Trigueros, Groeneveld, Moreno |
| Elche | 1 | Mojica | ||
| 23-sep-2021 | Granada | Granada | 2 | Sanchez, Milla (P) |
| Real Sociedad | 3 | Elustondo (2), Merino | ||
| 23-sep-2021 | Pamplona | Osasuna | 1 | Kike |
| Betis | 3 | Kike Hermoso, Juanmi, Willian Jose | ||
| 23-sep-2021 | Cadiz | Cadiz | 0 | |
| Barcelona | 0 | |||
| 7º Fecha | ||||
| 25-sep-2021 | Vitoria | Alaves | 1 | Laguardia |
| Atletico Madrid | 0 | |||
| 25-sep-2021 | Valencia | Valencia | 1 | Marcos Andre |
| Athletic Bilbao | 1 | Martinez | ||
| 25-sep-2021 | Sevilla | Sevilla | 2 | En-Nesyri, Mir |
| Español | 0 | |||
| 25-sep-2021 | Madrid | Real Madrid | 0 | |
| Villarreal | 0 | |||
| 26-sep-2021 | Palma | Mallorca | 2 | Rodriguez, Fer Niño |
| de Mallorca | Osasuna | 3 | Cote, Perez, Martinez | |
| 26-sep-2021 | Barcelona | Barcelona | 3 | Depay (P), L. De Jong, Fati |
| Levante | 0 | |||
| 26-sep-2021 | San Sebastian | Real Sociedad | 1 | Oyarzabal |
| Elche | 0 | |||
| 26-sep-2021 | Madrid | Rayo Vallecano | 3 | A. Garcia, R. Garcia, Isi Palazon |
| Cadiz | 1 | Haroyan | ||
| 26-sep-2021 | Sevilla | Betis | 2 | Willian Jose (2) |
| Getafe | 0 | |||
| 27-sep-2021 | Vigo | Celta | 1 | Suarez |
| Granada | 0 | |||
| 8º Fecha | ||||
| 1-oct-2021 | Bilbao | Athletic Bilbao | 1 | Garcia |
| Alaves | 0 | |||
| 2-oct-2021 | Pamplona | Osasuna | 1 | Sanchez |
| Rayo Vallecano | 0 | |||
| 2-oct-2021 | Palma | Mallorca | 1 | Angel |
| de Mallorca | Levante | 0 | ||
| 2-oct-2021 | Cadiz | Cadiz | 0 | |
| Valencia | 0 | |||
| 2-oct-2021 | Madrid | Atletico Madrid | 2 | Lemar, Suarez |
| Barcelona | 0 | |||
| 3-oct-2021 | Elche | Elche | 1 | Benedetto |
| Celta | 0 | |||
| 3-oct-2021 | Barcelona | Español | 2 | De Tomas, Vidal |
| Real Madrid | 1 | Benzema | ||
| 3-oct-2021 | Getafe | Getafe | 1 | Ramirez |
| Real Sociedad | 1 | Oyarzabal | ||
| 3-oct-2021 | Villarreal | Villarreal | 2 | Groeneveld (2) |
| Betis | 0 | |||
| 3-oct-2021 | Granada | Granada | 1 | Rochina |
| Sevilla | 0 | |||
| 9º Fecha | ||||
| 16-oct-2021 | Valencia | Valencia | 0 | |
| Getafe | 0 | |||
| 16-oct-2021 | San Sebastian | Real Sociedad | 1 | Lobete |
| Mallorca | 0 | |||
| 17-oct-2021 | Madrid | Rayo Vallecano | 2 | Hernandez, Nteka |
| Elche | 1 | Boye | ||
| 17-oct-2021 | Vigo | Celta | 0 | |
| Sevilla | 1 | Mir | ||
| 17-oct-2021 | Villarreal | Villarreal | 1 | Moreno |
| Osasuna | 2 | Torro, Avila | ||
| 17-oct-2021 | Barcelona | Barcelona | 3 | Fati, Depay (P), Philippe Coutinho |
| Valencia | 1 | Gaya | ||
| 18-oct-2021 | Vitoria | Alaves | 0 | |
| Betis | 1 | Iglesias | ||
| 18-oct-2021 | Barcelona | Español | 2 | De Tomas, Melamed |
| Cadiz | 0 | |||
| 1-dic-2021 | Madrid | Real Madrid | 1 | Benzema |
| Athletic Bilbao | 0 | |||
| 22-dic-2021 | Granada | Granada | 2 | Machis, Molina |
| Atletico Madrid | 1 | Joao Felix | ||
| 10º Fecha | ||||
| 22-oct-2021 | Pamplona | Osasuna | 1 | Avila |
| Granada | 1 | Montoro | ||
| 23-oct-2021 | Valencia | Valencia | 2 | Guedes, Gaya |
| Mallorca | 2 | Angel, Diakhaby (A) | ||
| 23-oct-2021 | Cadiz | Cadiz | 0 | |
| Alaves | 2 | Joselu (2, 1P) | ||
| 23-oct-2021 | Elche | Elche | 2 | Boye, Benedetto |
| Español | 2 | Manu, De Tomas | ||
| 23-oct-2021 | Bilbao | Athletic Bilbao | 2 | Garcia, Muniain (P) |
| Villarreal | 1 | Coquelin | ||
| 24-oct-2021 | Sevilla | Sevilla | 5 | Torres, Mir, Diego Carlos, Munir, Fernando |
| Levante | 3 | Morales (2), Melero | ||
| 24-oct-2021 | Barcelona | Barcelona | 1 | Agüero |
| Real Madrid | 2 | Alaba, Vazquez | ||
| 24-oct-2021 | Sevilla | Betis | 3 | Moreno, Juanmi, Willian Jose (P) |
| Rayo Vallecano | 2 | Nteka, Garcia | ||
| 24-oct-2021 | Madrid | Atletico Madrid | 2 | Suarez (2, 1P) |
| Real Sociedad | 2 | Sorloth, Isak | ||
| 25-oct-2021 | Getafe | Getafe | 0 | |
| Celta | 3 | Mina (2), Aspas | ||
| 11º Fecha | ||||
| 26-oct-2021 | Vitoria | Alaves | 1 | Loum |
| Elche | 0 | |||
| 26-oct-2021 | Barcelona | Español | 1 | De Tomas (P) |
| Athletic Bilbao | 1 | Williams | ||
| 26-oct-2021 | Villarreal | Villarreal | 3 | Torres, Dia, Groeneveld |
| Cadiz | 3 | Lozano (3) | ||
| 27-oct-2021 | Palma | Mallorca | 1 | Sanchez |
| de Mallorca | Sevilla | 1 | Lamela | |
| 27-oct-2021 | Madrid | Rayo Vallecano | 1 | Garcia |
| Barcelona | 0 | |||
| 27-oct-2021 | Sevilla | Betis | 4 | Iglesias (2, 1P), Pezzella, Juanmi |
| Valencia | 1 | Gabriel Paulista | ||
| 27-oct-2021 | Madrid | Real Madrid | 0 | |
| Osasuna | 0 | |||
| 28-oct-2021 | Vigo | Celta | 0 | |
| Real Sociedad | 2 | Isak, Elustondo | ||
| 28-oct-2021 | Granada | Granada | 1 | Molina |
| Getafe | 1 | Unal | ||
| 28-oct-2021 | Valencia | Levante | 2 | Bardhi (2P) |
| Atletico Madrid | 2 | Griezmann, Matheus Cunha | ||
| 12º Fecha | ||||
| 30-oct-2021 | Elche | Elche | 1 | Milla |
| Real Madrid | 2 | Vinicius Junior (2) | ||
| 30-oct-2021 | Sevilla | Sevilla | 2 | Diego Carlos, Ocampos |
| Osasuna | 0 | |||
| 30-oct-2021 | Valencia | Valencia | 2 | Guillamon, Soler (P) |
| Villarreal | 0 | |||
| 30-oct-2021 | Barcelona | Barcelona | 1 | Depay |
| Alaves | 1 | Rioja | ||
| 31-oct-2021 | Cadiz | Cadiz | 1 | Negredo (P) |
| Mallorca | 1 | Baba | ||
| 31-oct-2021 | Madrid | Atletico Madrid | 3 | Carrasco, Pezzella (A), Joao Felix |
| Betis | 0 | |||
| 31-oct-2021 | Getafe | Getafe | 2 | Unal (2) |
| Español | 1 | Gomez | ||
| 31-oct-2021 | San Sebastian | Real Sociedad | 1 | Isak (P) |
| Athletic Bilbao | 1 | Muniain | ||
| 1-nov-2021 | Madrid | Rayo Vallecano | 0 | |
| Celta | 0 | |||
| 1-nov-2021 | Valencia | Levante | 0 | |
| Granada | 3 | Sanchez, Suarez, Puertas | ||
| 13º Fecha | ||||
| 5-nov-2021 | Bilbao | Athletic Bilbao | 0 | |
| Cadiz | 1 | Salvi | ||
| 6-nov-2021 | Barcelona | Español | 2 | Pedrosa, De Tomas |
| Granada | 0 | |||
| 6-nov-2021 | Vigo | Celta | 3 | Aspas (2), Nolito |
| Barcelona | 3 | Fati, Busquets, Depay | ||
| 6-nov-2021 | Vitoria | Alaves | 2 | Joselu (2, 1P) |
| Levante | 1 | De Frutos | ||
| 6-nov-2021 | Madrid | Real Madrid | 2 | Kroos, Benzema |
| Rayo Vallecano | 1 | Garcia | ||
| 7-nov-2021 | Villarreal | Villarreal | 1 | Trigueros |
| Getafe | 0 | |||
| 7-nov-2021 | Valencia | Valencia | 3 | Savic (A), Duro (2) |
| Atletico Madrid | 3 | Suarez, Griezmann, Vrsaljko | ||
| 7-nov-2021 | Palma | Mallorca | 2 | Sevilla (P), Maffeo |
| de Mallorca | Elche | 2 | Boye (2) | |
| 7-nov-2021 | Pamplona | Osasuna | 0 | |
| Real Sociedad | 2 | Merino, Januzaj (P) | ||
| 7-nov-2021 | Sevilla | Betis | 0 | |
| Sevilla | 2 | Acuña, Bellerin (A) | ||
| 14º Fecha | ||||
| 19-nov-2021 | Valencia | Levante | 0 | |
| Athletic Bilbao | 0 | |||
| 20-nov-2021 | Vigo | Celta | 1 | Mendez |
| Villarreal | 1 | Moreno | ||
| 20-nov-2021 | Sevilla | Sevilla | 2 | Ocampos, Rakitic |
| Alaves | 2 | Laguardia, Joselu (P) | ||
| 20-nov-2021 | Madrid | Atletico Madrid | 1 | Felipe |
| Osasuna | 0 | |||
| 20-nov-2021 | Barcelona | Barcelona | 1 | Depay (P) |
| Español | 0 | |||
| 21-nov-2021 | Getafe | Getafe | 4 | Olivera, Cuenca, Unal, Mata |
| Cadiz | 0 | |||
| 21-nov-2021 | Granada | Granada | 1 | Suarez |
| Real Madrid | 4 | Asensio, Nacho, Vinicius Junior, Mendy | ||
| 21-nov-2021 | Elche | Elche | 0 | |
| Betis | 3 | Juanmi, Willian Jose (P), Fekir | ||
| 21-nov-2021 | San Sebastian | Real Sociedad | 0 | |
| Valencia | 0 | |||
| 22-nov-2021 | Madrid | Rayo Vallecano | 3 | Guardiola, Garcia, Trejo (P) |
| Mallorca | 1 | Prats | ||
| 15º Fecha | ||||
| 26-nov-2021 | Bilbao | Athletic Bilbao | 2 | Garcia, Luis Maximiano (A) |
| Granada | 2 | Machis, Molina | ||
| 27-nov-2021 | Vitoria | Alaves | 1 | Joselu |
| Celta | 2 | Mina, Aspas | ||
| 27-nov-2021 | Valencia | Valencia | 1 | Soler (P) |
| Rayo Vallecano | 1 | Isi Palazon | ||
| 27-nov-2021 | Palma | Mallorca | 0 | |
| de Mallorca | Getafe | 0 | ||
| 27-nov-2021 | Villarreal | Villarreal | 1 | Chukwueze |
| Barcelona | 3 | F. De Jong, Depay, Philippe Coutinho (P) | ||
| 28-nov-2021 | Sevilla | Betis | 3 | Juanmi (3) |
| Levante | 1 | Mustafi | ||
| 28-nov-2021 | Barcelona | Español | 1 | Herrera |
| Real Sociedad | 0 | |||
| 28-nov-2021 | Cadiz | Cadiz | 1 | Lozano |
| Atletico Madrid | 4 | Lemar, Griezmann, Correa, Matheus Cunha | ||
| 28-nov-2021 | Madrid | Real Madrid | 2 | Benzema, Vinicius Junior |
| Sevilla | 1 | Mir | ||
| 29-nov-2021 | Pamplona | Osasuna | 1 | Budimir (P) |
| Elche | 1 | Fidel | ||
| 16º Fecha | ||||
| 3-dic-2021 | Granada | Granada | 2 | Puertas, Arias |
| Alaves | 1 | Abram (A) | ||
| 4-dic-2021 | Sevilla | Sevilla | 1 | Ocampos |
| Villarreal | 0 | |||
| 4-dic-2021 | Barcelona | Barcelona | 0 | |
| Betis | 1 | Juanmi | ||
| 4-dic-2021 | Madrid | Atletico Madrid | 1 | Matheus Cunha |
| Mallorca | 2 | Russo, Kubo | ||
| 4-dic-2021 | San Sebastian | Real Sociedad | 0 | |
| Real Madrid | 2 | Vinicius Junior, Jovic | ||
| 5-dic-2021 | Madrid | Rayo Vallecano | 1 | Cabrera (A) |
| Español | 0 | |||
| 5-dic-2021 | Elche | Elche | 3 | Fidel (P), Morente, Fernandez |
| Cadiz | 1 | Alex | ||
| 5-dic-2021 | Valencia | Levante | 0 | |
| Osasuna | 0 | |||
| 5-dic-2021 | Vigo | Celta | 1 | Aspas |
| Valencia | 2 | Duro, Gomez | ||
| 6-dic-2021 | Getafe | Getafe | 0 | |
| Athletic Bilbao | 0 | |||
| 17º Fecha | ||||
| 10-dic-2021 | Palma | Mallorca | 0 | |
| de Mallorca | Celta | 0 | ||
| 11-dic-2021 | Barcelona | Español | 4 | Darder, De Tomas, Puado (2) |
| Levante | 3 | De Frutos, Son, Morales | ||
| 11-dic-2021 | Vitoria | Alaves | 1 | Joselu |
| Getafe | 1 | Unal | ||
| 11-dic-2021 | Valencia | Valencia | 2 | Guedes, Piccini |
| Elche | 1 | Boye | ||
| 11-dic-2021 | Bilbao | Athletic Bilbao | 0 | |
| Sevilla | 1 | Delaney | ||
| 12-dic-2021 | Villarreal | Villarreal | 2 | Mandi, Moreno (P) |
| Rayo Vallecano | 0 | |||
| 12-dic-2021 | Pamplona | Osasuna | 2 | Garcia, Avila |
| Barcelona | 2 | Gonzalez, Ezzalzouli | ||
| 12-dic-2021 | Sevilla | Betis | 4 | Moreno (2), Juanmi, Fekir |
| Real Sociedad | 0 | |||
| 12-dic-2021 | Madrid | Real Madrid | 2 | Benzema, Asensio |
| Atletico Madrid | 0 | |||
| 13-dic-2021 | Cadiz | Cadiz | 1 | Arzamandia |
| Granada | 1 | Molina | ||
| 18º Fecha | ||||
| 17-dic-2021 | Vigo | Celta | 3 | Mina, Aspas, Suarez |
| Español | 1 | Moron | ||
| 18-dic-2021 | Madrid | Rayo Vallecano | 2 | Guardiola, Catena |
| Alaves | 0 | |||
| 18-dic-2021 | San Sebastian | Real Sociedad | 1 | Isak |
| Villarreal | 3 | Moreno (2), Chukwueze | ||
| 18-dic-2021 | Barcelona | Barcelona | 3 | Jutgla, Gavi, Gonzalez |
| Elche | 2 | Morente, Milla | ||
| 18-dic-2021 | Sevilla | Sevilla | 2 | Rakitic, Ocampos |
| Atletico Madrid | 1 | Felipe | ||
| 19-dic-2021 | Granada | Granada | 4 | Molina (3), Puertas |
| Mallorca | 1 | Rodriguez | ||
| 19-dic-2021 | Bilbao | Athletic Bilbao | 3 | Williams (2), De Marcos |
| Betis | 2 | Juanmi, Fekir | ||
| 19-dic-2021 | Getafe | Getafe | 1 | Poveda |
| Osasuna | 0 | |||
| 19-dic-2021 | Madrid | Real Madrid | 0 | |
| Cadiz | 0 | |||
| 20-dic-2021 | Valencia | Levante | 3 | Campaña, Marti, Bardhi |
| Valencia | 4 | Gonçalo Guedes (2), Soler (2, 1P) | ||
| 19º Fecha | ||||
| 31-dic-2021 | Valencia | Valencia | 1 | Alderete |
| Español | 2 | De Tomas (P), Puado | ||
| 2-ene-2022 | Getafe | Getafe | 1 | Unal |
| Real Madrid | 0 | |||
| 2-ene-2022 | Madrid | Atletico Madrid | 2 | Correa (2) |
| Rayo Vallecano | 0 | |||
| 2-ene-2022 | Elche | Elche | 0 | |
| Granada | 0 | |||
| 2-ene-2022 | Vitoria | Alaves | 1 | Joselu (P) |
| Real Sociedad | 1 | Januzaj | ||
| 2-ene-2022 | Sevilla | Betis | 0 | |
| Celta | 2 | Aspas (2, 1P) | ||
| 2-ene-2022 | Palmas | Mallorca | 0 | |
| de Mallorca | Barcelona | 1 | De Jong | |
| 3-ene-2022 | Villarreal | Villarreal | 5 | Dia, Torres, Moreno (2), Trigueros |
| Levante | 0 | |||
| 3-ene-2022 | Pamplona | Osasuna | 1 | Kike |
| Athletic Bilbao | 3 | Sancet (3) | ||
| 3-ene-2022 | Cadiz | Cadiz | 0 | |
| Sevilla | 1 | Ocampos | ||
| 20º Fecha | ||||
| 8-ene-2022 | Valencia | Levante | 2 | Soldado, Morales |
| Mallorca | 0 | |||
| 8-ene-2022 | San Sebastian | Real Sociedad | 1 | Oyarzabal |
| Celta | 0 | |||
| 8-ene-2022 | Granada | Granada | 1 | Puertas |
| Barcelona | 1 | De Jong | ||
| 8-ene-2022 | Madrid | Real Madrid | 4 | Benzema (2, 1P), Vinicius Junior (2) |
| Valencia | 1 | Gonçalo Guedes | ||
| 9-ene-2022 | Madrid | Rayo Vallecano | 1 | Balliu |
| Betis | 1 | Canales | ||
| 9-ene-2022 | Sevilla | Sevilla | 1 | Mir |
| Getafe | 0 | |||
| 9-ene-2022 | Vitoria | Alaves | 0 | |
| Athletic Bilbao | 0 | |||
| 9-ene-2022 | Pamplona | Osasuna | 2 | Budimir, Barja |
| Cadiz | 0 | |||
| 9-ene-2022 | Villarreal | Villarreal | 2 | Torres, Moreno |
| Atletico Madrid | 2 | Correa, Kondogbia | ||
| 10-ene-2022 | Barcelona | Español | 1 | De Tomas (P) |
| Elche | 2 | Milla (2) | ||
| 21º Fecha | ||||
| 22-dic-2021 | Bilbao | Athletic Bilbao | 1 | Sancet |
| Real Madrid | 2 | Benzema (2) | ||
| 16-ene-2022 | Elche | Elche | 1 | Boye |
| Villarreal | 0 | |||
| 18-ene-2022 | Sevilla | Betis | 4 | Iglesias (2), Canales, Juanmi |
| Alaves | 0 | |||
| 18-ene-2022 | Cadiz | Cadiz | 2 | Negredo, Alejo |
| Español | 2 | Morlanes, De Tomas | ||
| 19-ene-2022 | Vigo | Celta | 2 | Mallo, Mina |
| Osasuna | 0 | |||
| 19-ene-2022 | Valencia | Valencia | 1 | Guedes |
| Sevilla | 1 | Diakhaby (A) | ||
| 20-ene-2022 | Getafe | Getafe | 4 | Ramirez, Unal, Maksimovic, Mayoral |
| Granada | 2 | Suarez (2) | ||
| 16-feb-2022 | Madrid | Atletico Madrid | 0 | |
| Levante | 1 | Melero | ||
| 2-mar-2022 | Palma | Mallorca | 0 | |
| de Mallorca | Real Sociedad | 2 | Silva, Merino | |
| 24-abr-2022 | Barcelona | Barcelona | 0 | |
| Rayo Vallecano | 1 | Garcia | ||
| 22º Fecha | ||||
| 21-ene-2022 | Barcelona | Español | 1 | De Tomas |
| Betis | 4 | Iglesias (2, 1P), Rodriguez, William Jose | ||
| 22-ene-2022 | Valencia | Levante | 0 | |
| Cadiz | 2 | Negredo, Salvi | ||
| 22-ene-2022 | Villarreal | Villarreal | 3 | Russo (A), Trigueros, Parejo (P) |
| Mallorca | 0 | |||
| 22-ene-2022 | Sevilla | Sevilla | 2 | Gomez, Torres |
| Celta | 2 | Cervi, Aspas | ||
| 22-ene-2022 | Madrid | Atletico Madrid | 3 | Matheus Cunha, Correa, Hermoso |
| Valencia | 2 | Musah, Duro | ||
| 23-ene-2022 | Granada | Granada | 0 | |
| Osasuna | 2 | Garcia, Kike | ||
| 23-ene-2022 | Madrid | Real Madrid | 2 | Modric (P), Eder Militao |
| Elche | 2 | Boye, Milla | ||
| 23-ene-2022 | San Sebastian | Real Sociedad | 0 | |
| Getafe | 0 | |||
| 23-ene-2022 | Madrid | Rayo Vallecano | 0 | |
| Athletic Bilbao | 1 | Serrano | ||
| 23-ene-2022 | Vitoria | Alaves | 0 | |
| Barcelona | 1 | De Jong | ||
| 23º Fecha | ||||
| 4-feb-2022 | Getafe | Getafe | 3 | Unal (2), Aleña |
| Levante | 0 | |||
| 5-feb-2022 | Elche | Elche | 3 | Milla (2), Fidel |
| Alaves | 1 | Joselu | ||
| 5-feb-2022 | Palma | Mallorca | 2 | Sevilla (P), Muriqi (P) |
| de Mallorca | Cadiz | 1 | Alcaraz | |
| 5-feb-2022 | Vigo | Celta | 2 | Mendez (2) |
| Rayo Vallecano | 0 | |||
| 5-feb-2022 | Pamplona | Osasuna | 0 | |
| Sevilla | 0 | |||
| 6-feb-2022 | Valencia | Valencia | 0 | |
| Real Sociedad | 0 | |||
| 6-feb-2022 | Barcelona | Barcelona | 4 | Alba, Gavi, Araujo, Dani Alves |
| Atletico Madrid | 2 | Carrasco, Suarez | ||
| 6-feb-2022 | Sevilla | Betis | 0 | |
| Villarreal | 2 | Torres, Capoue | ||
| 6-feb-2022 | Madrid | Real Madrid | 1 | Asensio |
| Granada | 0 | |||
| 7-feb-2022 | Bilbao | Athletic Bilbao | 2 | Sancet, Martinez |
| Español | 1 | Vilhena | ||
| 24º Fecha | ||||
| 11-feb-2022 | Sevilla | Sevilla | 2 | Gomez, Rafa Mir |
| Elche | 0 | |||
| 12-feb-2022 | Cadiz | Cadiz | 0 | |
| Celta | 0 | |||
| 12-feb-2022 | Villarreal | Villarreal | 0 | |
| Real Madrid | 0 | |||
| 12-feb-2022 | Madrid | Rayo Vallecano | 0 | |
| Osasuna | 3 | Moncayola, Garcia, Kike | ||
| 12-feb-2022 | Madrid | Atletico Madrid | 4 | Correa (2), Matheus Cunha, Hermoso |
| Getafe | 3 | Mayoral, Unal (2P) | ||
| 13-feb-2022 | Vitoria | Alaves | 2 | Loum, Joselu (P) |
| Valencia | 1 | Guedes (P) | ||
| 13-feb-2022 | Valencia | Levante | 2 | Gomez (2) |
| Betis | 4 | Fekir (2), Gonzalez, William Carvalho | ||
| 13-feb-2022 | San Sebastian | Real Sociedad | 2 | Oyarzabal (P), Rafinha |
| Granada | 0 | |||
| 13-feb-2022 | Barcelona | Español | 2 | Darder, De Tomas |
| Barcelona | 2 | Pedri, De Jong | ||
| 14-feb-2022 | Palma | Mallorca | 3 | Sevilla (P), Rodriguez, Simon (A) |
| de Mallorca | Athletic Bilbao | 2 | Garcia, Berenguer | |
| 25º Fecha | ||||
| 18-feb-2022 | Elche | Elche | 2 | Carrillo, Ponce |
| Rayo Vallecano | 1 | Garcia | ||
| 19-feb-2022 | Granada | Granada | 1 | Milla (P) |
| Villarreal | 4 | Groeneveld (3, 2P), Gomez | ||
| 19-feb-2022 | Pamplona | Osasuna | 0 | |
| Atletico Madrid | 3 | Joao Felix, Suarez, Correa | ||
| 19-feb-2022 | Cadiz | Cadiz | 1 | Negredo |
| Getafe | 1 | Mayoral (P) | ||
| 19-feb-2022 | Madrid | Real Madrid | 3 | Asensio, Vinicius Junior, Benzema (P) |
| Alaves | 0 | |||
| 20-feb-2022 | Barcelona | Español | 1 | Darder |
| Sevilla | 1 | Rafa Mir | ||
| 20-feb-2022 | Valencia | Valencia | 1 | Soler |
| Barcelona | 4 | Aubameyang (3), De Jong | ||
| 20-feb-2022 | Sevilla | Betis | 2 | Moreno, Willian Jose (P) |
| Mallorca | 1 | Muriqi | ||
| 20-feb-2022 | Bilbao | Athletic Bilbao | 4 | Vivian, Sancet, Williams, Muniain |
| Real Sociedad | 0 | Pedri, De Jong | ||
| 21-feb-2022 | Vigo | Celta | 1 | Cervi |
| Levante | 1 | Roger Marti | ||
| 26º Fecha | ||||
| 25-feb-2022 | Valencia | Levante | 3 | Morales, De Frutos, Melero |
| Elche | 0 | |||
| 26-feb-2022 | Palma | Mallorca | 0 | |
| de Mallorca | Valencia | 1 | Gabriel Paulista | |
| 26-feb-2022 | Getafe | Getafe | 2 | Unal (2) |
| Alaves | 2 | Escalante, Mendez | ||
| 26-feb-2022 | Madrid | Rayo Vallecano | 0 | |
| Real Madrid | 1 | Benzema | ||
| 26-feb-2022 | Madrid | Atletico Madrid | 2 | Renan Lodi (2) |
| Celta | 0 | |||
| 27-feb-2022 | Villarreal | Villarreal | 5 | Pino (4), Dia |
| Español | 1 | Bare | ||
| 27-feb-2022 | Sevilla | Sevilla | 2 | Rakitic (P), El Haddadi |
| Betis | 1 | Canales | ||
| 27-feb-2022 | San Sebastian | Real Sociedad | 1 | Elustondo |
| Osasuna | 0 | |||
| 27-feb-2022 | Barcelona | Barcelona | 4 | Aubameyang, Dembele, De Jong, Depay |
| Athletic Bilbao | 0 | |||
| 28-feb-2022 | Granada | Granada | 0 | |
| Cadiz | 0 | |||
| 27º Fecha | ||||
| 4-mar-2022 | Vitoria | Alaves | 0 | |
| Sevilla | 0 | |||
| 5-mar-2022 | Pamplona | Osasuna | 1 | Avila |
| Villarreal | 0 | |||
| 5-mar-2022 | Barcelona | Español | 2 | Cabrera, Cabaco (A) |
| Getafe | 0 | |||
| 5-mar-2022 | Valencia | Valencia | 3 | Gonçalo Guedes, Gomez, Soler (P) |
| Granada | 1 | Guillamon (A) | ||
| 5-mar-2022 | Madrid | Real Madrid | 4 | Camavinga, Modric, Benzema (P), Asensio |
| Real Sociedad | 1 | Oyarzabal (P) | ||
| 6-mar-2022 | Cadiz | Cadiz | 2 | Alcaraz, Idrissi |
| Rayo Vallecano | 0 | |||
| 6-mar-2022 | Elche | Elche | 1 | Fidel |
| Barcelona | 2 | Torres, Depay (P) | ||
| 6-mar-2022 | Vigo | Celta | 4 | Thiago Galhardo, Suarez, Aspas (2, 1P) |
| Mallorca | 3 | Gonzalez, Aidoo (A), Sevilla (P) | ||
| 6-mar-2022 | Sevilla | Betis | 1 | Tello |
| Atletico Madrid | 3 | Joao Felix (2), Lemar | ||
| 7-mar-2022 | Bilbao | Athletic Bilbao | 3 | Vesga, Williams, Zarraga (P) |
| Levante | 1 | De Frutos | ||
| 28º Fecha | ||||
| 11-mar-2022 | Madrid | Atletico Madrid | 2 | Joao Felix, De Paul |
| Cadiz | 1 | Negredo | ||
| 12-mar-2022 | Valencia | Levante | 1 | Gomez |
| Español | 1 | Puado | ||
| 12-mar-2022 | Granada | Granada | 0 | |
| Elche | 1 | Fidel | ||
| 12-mar-2022 | Villarreal | Villarreal | 1 | Parejo |
| Celta | 0 | |||
| 12-mar-2022 | Getafe | Getafe | 0 | |
| Valencia | 0 | |||
| 13-mar-2022 | Madrid | Rayo Vallecano | 1 | Bebe |
| Sevilla | 1 | Delaney | ||
| 13-mar-2022 | Sevilla | Betis | 1 | Iglesias |
| Athletic Bilbao | 0 | |||
| 13-mar-2022 | San Sebastian | Real Sociedad | 1 | Zubimendi |
| Alaves | 0 | |||
| 13-mar-2022 | Barcelona | Barcelona | 4 | Torres (2, 1P), Aubameyang, Puig |
| Osasuna | 0 | |||
| 14-mar-2022 | Palma | Mallorca | 0 | |
| de Mallorca | Real Madrid | 3 | Vinicius Junior, Benzema (2, 1P) | |
| 29º Fecha | ||||
| 18-mar-2022 | Bilbao | Athletic Bilbao | 1 | Berchiche |
| Getafe | 1 | Unal | ||
| 19-mar-2022 | Vitoria | Alaves | 2 | Escalante, Vallejo |
| Granada | 3 | Escudero, Puertas, Suarez | ||
| 19-mar-2002 | Elche | Elche | 0 | |
| Valencia | 1 | Gonçalo Guedes | ||
| 19-mar-2022 | Pamplona | Osasuna | 3 | Avila, Budimir, Brasanac |
| Levante | 1 | Marti | ||
| 19-mar-2022 | Madrid | Rayo Vallecano | 0 | |
| Atletico Madrid | 1 | Koke | ||
| 20-mar-2022 | Barcelona | Español | 1 | De Tomas |
| Mallorca | 0 | |||
| 20-mar-2022 | Vigo | Celta | 0 | |
| Betis | 0 | |||
| 20-mar-2022 | Cadiz | Cadiz | 1 | Sobrino |
| Villarreal | 0 | |||
| 20-mar-2022 | Sevilla | Sevilla | 0 | |
| Real Sociedad | 0 | |||
| 20-mar-2022 | Madrid | Real Madrid | 0 | |
| Barcelona | 4 | Aubameyang (2), Araujo, Torres | ||
| 30º Fecha | ||||
| 2-abr-2022 | Getafe | Getafe | 1 | Mayoral |
| Mallorca | 0 | |||
| 2-abr-2022 | Valencia | Levante | 2 | Morales (2) |
| Villarreal | 0 | |||
| 2-abr-2022 | Vigo | Celta | 1 | Nolito |
| Real Madrid | 2 | Benzema (2P) | ||
| 2-abr-2022 | Madrid | Atletico Madrid | 4 | Joao Felix (2), Suarez (2, 1P) |
| Alaves | 1 | Escalante | ||
| 3-abr-2022 | Bilbao | Athletic Bilbao | 2 | Berenguer, Villalibre |
| Elche | 1 | Ferrandez | ||
| 3-abr-2022 | Sevilla | Betis | 4 | Juanmi (2), William Carvalho, Moreno |
| Osasuna | 1 | Budimir | ||
| 3-abr-2022 | Granada | Granada | 2 | Molina, Milla (P) |
| Rayo Vallecano | 2 | Catena, Guardiola | ||
| 3-abr-2022 | Valencia | Valencia | 0 | |
| Cadiz | 0 | |||
| 3-abr-2022 | Barcelona | Barcelona | 1 | Pedri |
| Sevilla | 0 | |||
| 4-abr-2022 | San Sebastian | Real Sociedad | 1 | Isak (P) |
| Español | 0 | |||
| 31º Fecha | ||||
| 8-abr-2022 | Sevilla | Sevilla | 4 | Diego Carlos, Ocampos, Mir, Gomez |
| Granada | 2 | Machis, Diaz | ||
| 9-abr-2022 | Cadiz | Cadiz | 1 | Alejo |
| Betis | 2 | Tello, Iglesias (P) | ||
| 9-abr-2022 | Palma | Mallorca | 1 | Muriqi (P) |
| de Mallorca | Atletico Madrid | 0 | ||
| 9-abr-2022 | Villarreal | Villarreal | 1 | Pedraza |
| Athletic Bilbao | 1 | Garcia | ||
| 9-abr-2022 | Madrid | Real Madrid | 2 | Casemiro, Vazquez |
| Getafe | 0 | |||
| 10-abr-2022 | Pamplona | Osasuna | 1 | Budimir |
| Alaves | 0 | |||
| 10-abr-2022 | Barcelona | Español | 1 | Wu Lei |
| Celta | 0 | |||
| 10-abr-2022 | Elche | Elche | 1 | Carrillo |
| Real Sociedad | 2 | Sorloth, Le Normand | ||
| 10-abr-2022 | Valencia | Levante | 2 | Morales (P), Melero (P) |
| Barcelona | 3 | Aubameyang, Pedri, L. De Jong | ||
| 11-abr-2022 | Madrid | Rayo Vallecano | 1 | Guardiola |
| Valencia | 1 | Soler | ||
| 32º Fecha | ||||
| 15-abr-2022 | San Sebastian | Real Sociedad | 0 | |
| Betis | 0 | |||
| 16-abr-2022 | Elche | Elche | 3 | Mojica, Bigas, Lee Kang In (A) |
| Mallorca | 0 | |||
| 16-abr-2022 | Vitoria | Alaves | 1 | Joselu |
| Rayo Vallecano | 0 | |||
| 16-abr-2022 | Valencia | Valencia | 1 | Soler (P) |
| Osasuna | 2 | Avila (P), Budimir | ||
| 16-abr-2022 | Getafe | Getafe | 1 | Unal |
| Villarreal | 2 | Moreno, Trigueros | ||
| 17-abr-2022 | Granada | Granada | 1 | Collado |
| Levante | 4 | Gomez, Morales (P), Malsa, Soldado | ||
| 17-abr-2022 | Madrid | Atletico Madrid | 2 | Carrasco (2, 1P) |
| Español | 1 | De Tomas | ||
| 17-abr-2022 | Bilbao | Athletic Bilbao | 0 | |
| Celta | 2 | Aspas, Beltran | ||
| 17-abr-2022 | Sevilla | Sevilla | 2 | Eakitic, Lamela |
| Real Madrid | 3 | Rodrygo, Nacho, Benzema | ||
| 18-abr-2022 | Barcelona | Barcelona | 0 | |
| Cadiz | 1 | Perez | ||
| 33º Fecha | ||||
| 19-abr-2022 | Palma | Mallorca | 2 | Prats, Muriqi |
| de Mallorca | Alaves | 1 | Raillo (A) | |
| 19-abr-2022 | Sevilla | Betis | 0 | |
| Elche | 1 | Morente | ||
| 19-abr-2022 | Villarreal | Villarreal | 2 | Groeneveld (2, 1P) |
| Valencia | 0 | |||
| 20-abr-2022 | Madrid | Atletico Madrid | 0 | |
| Granada | 0 | |||
| 20-abr-2022 | Vigo | Celta | 0 | |
| Getafe | 2 | Mayoral (2) | ||
| 20-abr-2022 | Pamplona | Osasuna | 1 | Budimir |
| Real Madrid | 3 | Alaba, Asensio, Vazquez | ||
| 21-abr-2022 | Barcelona | Español | 0 | |
| Rayo Vallecano | 1 | Guardiola | ||
| 21-abr-2022 | Valencia | Levante | 2 | Morales (P), Soldado |
| Sevilla | 3 | Corona (2), Kounde | ||
| 21-abr-2022 | Cadiz | Cadiz | 2 | Perez, Sobrino |
| Athletic Bilbao | 3 | Garcia, Muniain, Vesga | ||
| 21-abr-2022 | San Sebastian | Real Sociedad | 0 | |
| Barcelona | 1 | Aubameyang | ||
| 34º Fecha | ||||
| 29-abr-2022 | Sevilla | Sevilla | 1 | En Nesyri |
| Cadiz | 1 | Perez | ||
| 30-abr-2022 | Vitoria | Alaves | 2 | Laguardia, Escalante |
| Villarreal | 1 | Chukwueze | ||
| 30-abr-2022 | Madrid | Real Madrid | 4 | Rodrygo (2), Asensio, Benzema |
| Español | 0 | |||
| 30-abr-2022 | Valencia | Valencia | 1 | Duro |
| Levante | 1 | Duarte | ||
| 30-abr-2022 | Bilbao | Athletic Bilbao | 2 | Hermoso (A), Williams (P) |
| Atletico Madrid | 0 | |||
| 1-may-2022 | Elche | Elche | 1 | Milla |
| Osasuna | 1 | Budimir (P) | ||
| 1-may-2022 | Granada | Granada | 1 | Machis |
| Celta | 1 | Aspas | ||
| 1-may-2022 | Madrid | Rayo Vallecano | 1 | Garcia |
| Real Sociedad | 1 | Sorloth | ||
| 1-may-2022 | Barcelona | Barcelona | 2 | Depay, Busquets |
| Mallorca | 1 | Raillo | ||
| 2-may-2022 | Getafe | Getafe | 0 | |
| Betis | 0 | |||
| 35º Fecha | ||||
| 6-may-2022 | Valencia | Levante | 2 | Miramon, Melero (P) |
| Real Sociedad | 1 | Silva | ||
| 7-may-2022 | Palma | Malo | 2 | Sevilla, Raillo |
| de Mallorca | Granada | 6 | Suarez, Escudero, Puertas, Molina (2), Uzumi | |
| 7-may-2022 | Bilbao | Athletic Bilbao | 0 | |
| Valencia | 0 | |||
| 7-may-2022 | Vigo | Celta | 4 | Thiago Galhardo, Aspas (2), Cervi |
| Alaves | 0 | |||
| 7-may-2022 | Cadiz | Cadiz | 3 | Negredo, Sobrino, Lozano |
| Elche | 0 | |||
| 7-may-2022 | Sevilla | Betis | 1 | Bartra |
| Barcelona | 2 | Fati, Alba | ||
| 8-may-2022 | Getafe | Getafe | 0 | |
| Rayo Vallecano | 0 | |||
| 8-may-2022 | Villarreal | Villarreal | 1 | Lo Celso |
| Sevilla | 1 | Kounde | ||
| 8-may-2022 | Barcelona | Español | 1 | Melamed |
| Osasuna | 1 | Barja | ||
| 8-may-2022 | Madrid | Atletico Madrid | 1 | Carrasco (P) |
| Real Madrid | 0 | |||
| 36º Fecha | ||||
| 10-may-2022 | Valencia | Valencia | 0 | |
| Betis | 3 | Willian Jose, Canales, Iglesias | ||
| 10-may-2022 | Granada | Granada | 1 | Collado |
| Athletic Bilbao | 0 | |||
| 10-may-2022 | Barcelona | Barcelona | 3 | Depay, Aubameyang (2) |
| Celta | 1 | Aspas | ||
| 11-may-2022 | Vitoria | Alaves | 2 | De la Fuente, Escalante |
| Español | 1 | De Tomas (P) | ||
| 11-may-2022 | Pamplona | Osasuna | 1 | Oier |
| Getafe | 1 | Torro (A) | ||
| 11-may-2022 | Sevilla | Sevilla | 0 | |
| Mallorca | 0 | |||
| 11-may-2022 | Elche | Elche | 0 | |
| Atletico Madrid | 2 | Matheus Cunha, De Paul | ||
| 12-may-2022 | San Sebastian | Real Sebastian | 3 | Sorloth, Januzaj (P), Portu (P) |
| Cadiz | 0 | |||
| 12-may-2022 | Madrid | Rayo Vallecano | 1 | Guardiola |
| Villarreal | 5 | Pedraza (2), Foyth, Alcacer, Torres | ||
| 12-may-2022 | Madrid | Real Madrid | 6 | Mendy, Benzema, Rodrygo, Vinicius Junior (3) |
| Levante | 0 | |||
| 37º Fecha | ||||
| 14-may-2022 | Barcelona | Español | 1 | De Tomas |
| Valencia | 1 | Gomez | ||
| 15-may-2022 | Bilbao | Athletic Bilbao | 2 | Berenguer, Villalibre |
| Osasuna | 0 | |||
| 15-may-2022 | Madrid | Atletico Madrid | 1 | Gimenez |
| Sevilla | 1 | En Nesyri | ||
| 15-may-2022 | Sevilla | Betis | 2 | Juanmi (2) |
| Granada | 0 | |||
| 15-may-2022 | Vigo | Celta | 1 | Suarez |
| Elche | 0 | |||
| 15-may-2022 | Palma | Mallorca | 2 | Muriqi, Prats |
| de Mallorca | Rayo Vallecano | 1 | Ciss | |
| 15-may-2022 | Getafe | Getafe | 0 | |
| Barcelona | 0 | |||
| 15-may-2022 | Cadiz | Cadiz | 1 | Sobrino |
| Real Madrid | 1 | Diaz | ||
| 15-may-2022 | Valencia | Levante | 3 | Duarte, Marti, Morales |
| Alaves | 1 | Joselu | ||
| 15-may-2022 | Villarreal | Villarreal | 1 | Coquelin |
| Real Sociedad | 1 | Isak, Zubimendi | ||
| 38º Fecha | ||||
| 20-may-2022 | Madrid | Real Madrid | 0 | |
| Betis | 0 | |||
| 20-may-2022 | Madrid | Rayo Vallecano | 2 | Garcia, Guardiola (P) |
| Levante | 4 | Melero (2), Marti, Moreno | ||
| 21-may-2022 | Valencia | Valencia | 2 | Gomez, Araujo (A) |
| Celta | 0 | |||
| 22-may-2022 | Elche | Elche | 3 | Olaza, Perez (2) |
| Getafe | 1 | Unal | ||
| 22-may-2022 | Vitoria | Alaves | 0 | |
| Cadiz | 1 | Lozano | ||
| 22-may-2022 | Granada | Granada | 0 | |
| de Mallorca | Español | 0 | ||
| 22-may-2022 | Pamplona | Osasuna | 0 | |
| Mallorca | 2 | Angel, Grenier | ||
| 22-may-2022 | Barcelona | Barcelona | 0 | |
| Villarreal | 2 | Pedraza, Gomez | ||
| 22-may-2022 | San Sebastian | Real Sociedad | 1 | Guridi |
| Atletico Madrid | 2 | De Paul, Correa | ||
| 22-may-2022 | Sevilla | Sevilla | 1 | Mir |
| Athletic Bilbao | 0 | |||